# Retatrutide

Retatrutide, development code LY3437943, is a synthetic peptide of 39 amino acids with an amide (-NH2) at the end of the chain. Its molecular formula is C221H342N46O68 and its molecular weight is 4731.3.

Three of its building blocks are not found in natural proteins. Positions 2 and 20 are α-aminoisobutyric acid (Aib), which carries two methyl groups where most amino acids have one hydrogen. Position 13 is α-methyl-leucine, a leucine with an extra methyl group. Both make the chain stiffer and harder for enzymes to cut.

The lysine at position 17 carries a side chain attached to its amine group. The side chain has three parts, joined in a row: a short linker called AEEA (a small amino acid with a two-unit ethylene glycol spacer), a γ-glutamic acid, and eicosanedioic acid, a 20-carbon chain with an acid group at each end. The side chain adds about 600 to the molecule's weight, so check the mass on the certificate of analysis against the full structure, not just the amino acid chain.

Supplied as a freeze-dried (lyophilised) powder in a sealed glass vial. For laboratory research use only. Not for human or veterinary use.

- URL: https://amidae.com/products/retatrutide
- Availability: In stock
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## Technical data

- Sequence: Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-αMeLeu-Leu-Asp-Lys-Lys(eicosanedioyl-γGlu-AEEA)-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
- Molecular formula: C221H342N46O68
- Molecular weight: 4731.3 g/mol
- Monoisotopic mass: 4728.4718 Da
- Synonyms: LY3437943
- CAS number: 2381089-83-2
- PubChem CID: 171390338
- InChIKey: MLOLQJNKXBNWFW-SAGGEDDASA-N
- Form: Lyophilised powder
- Storage: Store at -20 °C, sealed and protected from light
- Safety data sheet: on request (https://amidae.com/contact)

## Variants

| Options | SKU | Price | Availability | Variant ID |
| --- | --- | --- | --- | --- |
| Size: 10 mg vial | AMI-RETATRUTIDE-10 | £44.95 | In stock | `variant_01M6EFZT96F4B42Z8HG64EHSAX` |

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