
MOTS-c
C101H152N28O22S22174.6 g/molCAS 1627580-64-6
MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c) is a 16-residue peptide encoded by a short open reading frame within the mitochondrial 12S rRNA gene. It was first described by Lee et al. in 2015 and belongs to the small group of mitochondrial-derived peptides that also includes humanin. Supplied as a lyophilised powder in a sealed glass vial. For laboratory research use only. Not for human or veterinary use.
At a glance
- Sequence
- H-MRWQEMGYIFYPRKLR-OH
- Amount
- 10 mg per vial
- Form
- Lyophilised powder
- Storage
- Store at -20 °C, sealed and protected from light
Full technical data
Specification
- Sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-ArgCalculate pI and charge
- CAS number
- 1627580-64-6
- Molecular formula
- C101H152N28O22S2
- Molecular weight
- 2174.6 g/mol
- Form
- Lyophilised powder
- Storage
- Store at -20 °C, sealed and protected from light
Names and identifiers
- Synonyms
- Mitochondrial open reading frame of the 12S rRNA type-c
- One-letter code
- H-MRWQEMGYIFYPRKLR-OH
- InChIKey
- WYTHCOXVWRKRAH-LOKRTKBUSA-N
- PubChem CID
- 146675088
Documents
- Safety data sheetOn request
References
- Kim KH et al. (2018). The Mitochondrial-Encoded Peptide MOTS-c Translocates to the Nucleus to Regulate Nuclear Gene Expression in Response to Metabolic Stress. Cell Metab.
- Benayoun BA and Lee C (2019). MOTS-c: A Mitochondrial-Encoded Regulator of the Nucleus. Bioessays.
- Lee C (2019). Nuclear transcriptional regulation by mitochondrial-encoded MOTS-c. Mol Cell Oncol.
How to cite this product
MOTS-c (Amidae, United Kingdom; lot [lot number]). https://amidae.com/products/mots-c
Add the vial size and the lot number from the vial label. Each lot's COA page gives the complete citation.
Structure
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