SS-31
C32H49N9O5639.8 g/molCAS 736992-21-5
SS-31£49.95
SS-31, also known as elamipretide and MTP-131, is a synthetic tetrapeptide from the Szeto–Schiller family of aromatic-cationic peptides. Its sequence, D-Arg-Dmt-Lys-Phe-NH2, alternates basic and aromatic residues. It includes 2′,6′-dimethyltyrosine (Dmt), a non-proteinogenic amino acid, and a C-terminal amide, and carries a net charge of 3+ at neutral pH. Supplied as a lyophilised powder in a sealed glass vial. For laboratory research use only. Not for human or veterinary use.
At a glance
- Sequence
- D-Arg-Dmt-Lys-Phe-NH2
- Amount
- 10 mg per vial
- Form
- Lyophilised powder
- Storage
- Store at -20 °C, sealed and protected from light
Full technical data
Specification
- Sequence
- D-Arg-Dmt-Lys-Phe-NH2Calculate pI and charge
- CAS number
- 736992-21-5
- Molecular formula
- C32H49N9O5
- Molecular weight
- 639.8 g/mol
- Form
- Lyophilised powder
- Storage
- Store at -20 °C, sealed and protected from light
Names and identifiers
- Synonyms
- Elamipretide
- MTP-131
- Szeto–Schiller peptide 31
- InChIKey
- SFVLTCAESLKEHH-WKAQUBQDSA-N
- PubChem CID
- 11764719
Documents
- Safety data sheetOn request
References
- Mitchell W et al. (2020). The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action. J Biol Chem.
- Chavez JD et al. (2020). Mitochondrial protein interaction landscape of SS-31. Proc Natl Acad Sci U S A.
- Tamucci JD et al. (2023). Peptide Power: Mechanistic Insights into the Effect of Mitochondria-Targeted Tetrapeptides on Membrane Electrostatics from Molecular Simulations. Mol Pharm.
How to cite this product
SS-31 (Amidae, United Kingdom; lot [lot number]). https://amidae.com/products/ss-31
Add the vial size and the lot number from the vial label. Each lot's COA page gives the complete citation.
Structure
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